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Is AstraZeneca on track to meet its $80B revenue target?

LONDON — In 2024, AstraZeneca’s CEO Pascal Soriot set a new goal: for the company to pull in $80 billion in annual sales by 2030. At that time, this target looked ambitious. But ...

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NIH stops low-dose Xarelto arm of large stroke study due to safety concerns

The National Institutes of Health has halted an arm of a large trial investigating whether J&J and Bayer's blood thinner Xarelto is superior to the standard of care for lowering the rate of stroke...

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AbbVie, AstraZeneca lose appeal in Louisiana 340B contract pharmacy fight

A US appeals court upheld a Louisiana law regulating how 340B-discounted drugs are distributed to patients, dealing another setback to the pharma industry as drugmakers continue fighting state...

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ILiAD raises $115M round to advance whooping cough vaccine

It isn’t all doom and gloom in the vaccine industry. ILiAD Biotechnologies announced a $115 million oversubscribed Series B on Tuesday — enough money to start accruing pivotal Phase 3 data of ...

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Isomorphic claims major advance with new AI drug design engine

Nearly two years ago, Isomorphic Labs dropped AlphaFold 3, the latest generation of its Nobel Prize-winning, structure-predicting AI model. Now the company claims it has another major advance on its...

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Moderna accuses FDA of shifting standard as agency refuses flu shot review

The FDA said it won't review Moderna’s flu vaccine application, a surprise decision that the company is describing as a shifting of the standards for its pivotal trial well after it thought it had...

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Upstream Bio's stock slides on Phase 2 severe asthma data for verekitug

Upstream Bio on Wednesday said its TSLP-targeting drug met its goal in a mid-stage trial in severe asthma, which is a step forward in its bid to challenge Dupixent and Tezspire down the line. ...

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Sanofi invests in China startup GluBio in developing molecular glue for...

A small startup based in San Diego and Shanghai believes it has figured out how to boost hemoglobin levels with a pill, potentially offering a cheaper and simpler alternative to expensive and onerous...

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Post-Hoc Live: Is biotech’s relationship with the FDA at a breaking point? 

For years, the wisdom in biopharma was that you don’t pick a fight with the FDA in public. But that’s changed over the last year, as biopharma companies have become increasingly critical of what they...

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Oscar Health expects explosive growth for 2026, but it comes with a risk

Oscar Health added more than a million new members to its insurance rolls during the recent open enrollment period, fueling what it projects to be massive growth for 2026. When reporting 2025 results...

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How a closet full of EKG machines illustrates pharma’s clinical trial cost...

When Jake Van Naarden visits a hospital running clinical trials, he runs into an odd sight. Van Naarden, the head of Eli Lilly's oncology unit, opens a supply closet and sees more than a dozen ...

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Gubra forms venture unit; Galecto's $275M offering

Plus, news about THX Pharma and Biocodex: 🏗️ Gubra's venture unit: The Danish biotech and CRO operator, which is partnered with AbbVie and Boehringer Ingelheim, has created Gubra Ventures to build ...

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Madrigal pads MASH pipeline with six siRNAs from China's Ribo

Madrigal Pharmaceuticals is on a mission to become a generational, independent player in the MASH field with its third deal in eight months. The first FDA-approved medicine for the fatty liver disease,...

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After CEO departs, CSL details profit crash, $1.1B impairment costs 

One day after bumping out CEO Paul McKenzie, Australia’s CSL revealed what he left behind: declining profit and a $1.1 billion hole due to lower US vaccine demand and increased generic competition. CSL

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Prasad overruled vaccine review team, office director on Moderna flu shot

Vinay Prasad, director of the FDA's office of biologics and vaccines, overruled both the vaccine review team and the head of the FDA's vaccine team as part of the ...

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Former AstraZeneca senior staff charged with illegal trade in China

Chinese prosecutors have charged two of AstraZeneca’s former senior employees with illegal trade, unlawful collection of personal information, and medical insurance fraud, the company said this week....

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FDA may consider Moderna's flu vaccine in a narrower group

The FDA may be more willing to look at Moderna’s mRNA-based flu vaccine if the company re-filed it for a narrower group of older adults, a senior agency official told reporters in a call Wednesday ...

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Hinge Health is looking to build AI tools for mental health support

Hinge Health is building an AI-powered mental health platform alongside its virtual physical therapy services, according to job listings Endpoints News viewed. Among the listings, the company is...

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Updated: Sanofi's Paul Hudson out, with Belén Garijo to step in as new CEO

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European VCs form coalition to get more support for biotech investing

Some of Europe's largest biotech investors are banding together in an effort to drive more private and public capital toward homegrown medicines and startups. Novo Holdings, Forbion, Sofinnova...

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