Silence reports Phase 1 data from rare blood disorder trial
Silence Therapeutics touted Phase 1 data from an ongoing study Thursday morning in patients with a rare disease where their bone marrow produces too many red blood cells. The results, which come from a...
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AbbVie buys Third Rock's Celsius for $250M to expand IBD pipeline
As AbbVie continues to tout its next generation of immunology drugs behind Humira, it’s buying an early-stage startup to boost its longer-term prospects in inflammatory bowel disease. The Chicago-area...
View ArticleRecursion’s $200M offering; Sanofi invests $40M in Vigil Neuroscience
Plus, news about 2seventy, Novo Nordisk, CASI, CalciMedica, X4, NeOnc, ANI, Alimera, Holoclara, Nxera, Future Pak, Vanda and Bayer: Recursion Pharmaceuticals is selling $200M in shares: The company is...
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Biogen is pursuing more dealmaking this year, with plans to spend up to $8B
Biogen appears to be subtly signaling it has a larger appetite for M&A than previously stated. In an exclusive interview with Endpoints News, Biogen head of corporate development Adam Keeney said...
View ArticleSK Bioscience takes majority stake in CDMO for $244M; Ex-Lonza CEO joins Cytiva
Welcome to Endpoints News’ manufacturing briefs, where we bring you essential news on new builds, collaborations, recalls and more. SK Bioscience now has a 60% stake in the CDMO IDT Biologika after...
View ArticleGSK’s manufacturing sites in Singapore will use 100% renewable energy by 2025
GSK said it is on track to convert its global manufacturing sites into using renewable electricity, with its facilities in Singapore becoming the latest to make the transition. The UK pharma has signed...
View ArticleGrail pioneered multi-cancer tests. But the company’s rough public debut...
Is Grail’s lurching start as a newly public company a bad omen for what some view as the future of cancer testing? In its first week of trading since being spun off from Illumina, investors have valued...
View ArticleTo tackle a deadly brain disease, scientists devise small but charming...
Researchers from MIT and Harvard have crafted a new tool to silence genes without editing their sequence and are using it to develop a treatment for prion disease, a fatal neurodegenerative condition...
View ArticleSupreme Court narrowly rejects Purdue bankruptcy plan, says it gives Sacklers...
The Supreme Court ruled against Purdue Pharma’s bankruptcy plan on Thursday, denying protection for the Sackler family from a “broad sweep of present and future claims” over their role in the opioid...
View ArticleWhat Coherus' $40M sale of its Humira biosimilar says about the crowded market
Coherus BioSciences is selling its Humira biosimilar for just $40 million, only three years after it won FDA approval, showing just how crowded the market has become for Humira and its nine biosimilar...
View ArticleHouse panel advances bill to allow Medicare to cover obesity drugs
The House Ways and Means Committee on Thursday cleared a bill that would direct Medicare to cover obesity treatments — but only for a small sliver of beneficiaries. The committee voted 36-4 to pass an...
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Lykos takes another hit as ICER lays out 'insufficient' evidence for...
A key independent drug pricing organization has concluded that the available evidence for Lykos Therapeutics’ MDMA-assisted psychotherapy is “insufficient” and it can’t be compared to other...
View ArticleImmunology biotech Alumis secures $250M in shrunken IPO
Alumis, an immunology drug developer on the cusp of Phase 3, will go public Friday in a smaller IPO than it originally projected. The Bay Area startup sold 13.12 million shares $ALMS at $16 apiece to...
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Autoimmune brain disease startup Arialys gets new leader; Intellia, Arvinas...
Peter Flynn Peter Flynn has taken the helm from Avalon BioVentures managing partner Jay Lichter at Arialys Therapeutics, a startup that is developing treatments in the field of immunoneuropsychiatry —...
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FDA rejects Rocket Pharma’s ultra-rare immune disease gene therapy over...
The FDA rejected Rocket Pharmaceuticals’ gene therapy for leukocyte adhesion deficiency-I (LAD-I), requesting “limited additional” manufacturing information. The company announced the rejection on...
View ArticleSavara’s $100M offering; New biotech to test Eisai drug in Ph2
Plus, news about Daiichi Sankyo, Seagen, Lantheus, Life Molecular Imaging, Astellas Gene Therapies, Eli Lilly and Aparito: Savara prices $100M offering: The Langhorne, PA-based biotech will secure...
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J&J details Phase 3 success of autoimmune disease drug, touting broader range...
Johnson & Johnson’s experimental autoimmune treatment lowered the impact of myasthenia gravis on daily life compared to placebo in antibody-positive patients in a late-stage study. The drug is part...
View ArticleRovi teases acquisition offers for its CDMO unit potentially worth €2B to €3B
Rovi has attracted multiple buyout bids for its contract manufacturing business after the company said it was weighing its options for the division several months ago. The Spanish drugmaker said...
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Why BARDA is handing out hundreds of millions of dollars to long-shot...
In 2023, Vaxart halted work on its oral vaccine for Covid-19, and didn’t even have enough money to finish 2024. Now, the US government is lending a big hand. The Biomedical Advanced Research and...
View ArticleWhy the Supreme Court's overrule of Chevron has major implications for the FDA
The Supreme Court on Friday overruled a longstanding legal doctrine that gives federal agencies latitude to interpret federal law, which legal scholars and industry have warned could destabilize the...
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