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Novo turns to Septerna for oral obesity medicines in deal worth up to $2.2B

Novo Nordisk continues to sling obesity drug partnerships. Its latest biotech of choice is Septerna, which will help the Danish pharma make oral small molecules. Novo will give over $200 million in...

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GSK to pay $1.2B upfront to snag Boston Pharma’s mid-stage MASH hope

GSK will hand over $1.2 billion in upfront cash to license a closely-watched candidate for fatty liver disease from Boston Pharmaceuticals. The drug in question is Boston Pharma’s lead asset,...

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AbbVie doubles down on siRNA with $335M upfront bet on ADARx

After getting into siRNA work with its $1.4 billion acquisition of Aliada Therapeutics late last year, AbbVie is beefing up its presence in the hot subfield of genetic medicines. On Wednesday, AbbVie ...

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SK, Carlyle bolster bluebird bio bid; Therini Bio raises $39M

Plus, news about Allogene, Kyverna, Sernova, ADC Therapeutics, Acelyrin, Alumis, Atara, Lava Therapeutics and Repare Therapeutics: SK, Carlyle offer more upfront cash to bluebird bio shareholders:...

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FDA gives AbbVie accelerated approval for antibody-drug conjugate in lung cancer

The FDA approved a new antibody-drug conjugate from AbbVie on Wednesday to treat patients with certain kinds of lung cancer. Regulators granted accelerated approval to telisotuzumab vedotin in...

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Sanofi touts $20B investment in US over five years

Sanofi announced plans to invest “at least” $20 billion in the US through 2030, following similar commitments made by several pharma companies. The company said Wednesday that the investment includes...

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Ex-FDA chief Robert Califf thinks RFK Jr.'s vaccine opinions are relevant

HHS Secretary Robert F. Kennedy Jr. told a House committee Wednesday morning that he believed his opinions on vaccines were “irrelevant,” prompting a rebuke from a former top US health official. The...

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RFK Jr. defends HHS staff cuts at two congressional hearings

HHS Secretary Robert F. Kennedy Jr. faced hours of congressional grilling on Wednesday over his proposed budget cuts and planned overhaul of the agency that’s expected to shrink the workforce by 20,000...

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Hengrui, one of China's leading biotechs, anticipates $1.2B in proposed Hong...

Jiangsu Hengrui, a 55-year-old drugmaker that has become one of China's leading forces in biotech, expects net proceeds of about 9.4 billion Hong Kong dollars ($1.2 billion) from its proposed float on...

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Biohaven stock sinks on three-month delay for neuro drug's FDA approval decision

Biohaven said late Wednesday that the FDA would be delaying the PDUFA date for its neurodegenerative disease therapy troriluzole and will also require an advisory committee meeting to review the drug....

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Merck KGaA Q1 earnings: Tariff surcharge for US customers will continue

Despite pausing a tariff surcharge for China-based clients, Merck KGaA will carry on with adding an extra charge for US customers to account for President Donald Trump’s levies. “What we're doing is we...

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Exclusive: Datavant will acquire Aetion, double life sciences team

The health tech company Datavant is acquiring Aetion, a rival in the real-world data space, Endpoints News exclusively reports. Datavant on Thursday plans to announce the deal, which will double the...

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Abundant Venture Partners teams up with 17 health systems to develop tech

Seventeen health systems have signed up for a venture firm to help them vet which health tech companies to adopt and invest in, as more hospitals look towards a more concierge-style approach to...

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Empower Pharmacy allegedly used low-quality ingredients, skirted rules

A company that calls itself the US’ “largest and most advanced” compounding pharmacy — and whose business has exploded thanks to demand for popular weight loss drugs — has used poor-quality...

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AGC Bio secures lentiviral contract; Thermo Fisher to make Cybin asset

Welcome to Endpoints News’ manufacturing briefs, where we bring you essential news on new builds, collaborations, recalls and more. AGC Biologics is partnering with Quell Therapeutics, the companies...

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Pathos AI collects $365M to fuel data-driven oncology studies

Pathos AI, seeking to upend cancer drug development with artificial intelligence and large multimodal models, has raised the third-largest private funding round in biotech so far this year. In the...

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Enliven stops work on solid tumor drug; Pulmatrix to divest assets

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Bristol Myers CEO says America’s biopharma pole position is not guaranteed

NEW YORK — Bristol Myers Squibb CEO Chris Boerner said America’s role as the global biopharma leader is at a “pivot point” as the Trump administration aims to remake the country’s institutions and...

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FDA warns Mayne Pharma over 'misleading' birth control pill claims

The FDA’s drug promotion office is calling out Australia's Mayne Pharma for making “false or misleading claims” about the benefits and risks of its birth control pill Nextstellis. The agency's

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Philadelphia doctors treat infant with first custom CRISPR therapy that fixes...

PHILADELPHIA — Soon after Kyle Patrick Muldoon, Jr. was born in August 2024, his doctors knew something was wrong. KJ, as his parents call him, was too tired to feed, his ...

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